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Mary Janesolicitou a tradução 8 лет назад
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Because the FH protein regulates the conversion of fumarate to malate in the citric acid (Krebs) cycle, the inactivation of this protein increases the level of fumarate, which competitively inhibits the HIF (hypoxia-inducible factors) prolyl hydroxylase.

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  1. 1.

    Так как белок-фермент фумарат гидратаза регулирует превращение фумарата до малеата в цикле трикарбоновых кислот Кребса, инактивация данного протеина приводит к увеличению уровня фумарата, который конкурентно ингибирует индуцируемый гипоксией фактор фермент пролил-гидроксилазу.

    Tradução adicionada por Vladislav Jeong
    Ouro en-ru
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